In February 2005, during a training in Shadow island, near Alaska coasts , a genetically modified soldier group under the order of Fox Hound unity make a rebellion and take the control of nuclear settlements.

Their leader, Liquid Snake, threatens the White House by a nuclear shot if the leftover of Big Boss, biggest soldier of the twentieth century and a billion dollar is not given.

Homeland security minister, Roy Campbell, former commandant of Fox Hound comes back from retirement and asks Solid Snake, an elite shooter to help him save hostages and stop the nuclear threat.

Solid Snake has to enter the complex helped by distance by a specialist team composed of Campbell, Mei Ling, Naomi Hunter, Nastasha Romanenko and Master Miller.


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